[LCSB] Three systems biology lectures

[Gunnar Cedersund]

Dear colleagues and fellow systems biologists,


The autumn has started, and it is again time for lectures in the systems biology seminar series. First out are two guests from Gothenburg and Stuttgart. The main lectures are as usual on Mondays at 15.30-17, but note that Jan Hasenauer also has an additional tutorial for hands-on guidance into his new toolbox on set-based model analysis next Friday. More lectures will be announced soon, and up-to-date information including links, maps, etc is always available at http://www.liu.se/forskning/lcsb/upcoming-events?l=sv


September 13, 15.30-17, Martin Adiels, Gothenburg University, "Whole-body models for fatty acid homeostasis", Hälsans hus, lärosal 1

September 17, 10.15-12, Jan Hasenauer, University of Stuttgart,  "Tutorial in the set-identification matlab toolbox", HUB8, (in the HU library).

September 20, 15.30-17, Jan Hasenauer, University of Stuttgart, "Guaranteed predictions in spite of limited knowledge and uncertainties? - A case study for the NF-kB signaling pathway", Glashuset, B-house, Campus Valla
      Abstract:
      The main goal of system biology is a quantitative description of cellular processes and the understanding of those. Unfortunately, achieving this aim is rather difficult, as models of biological systems are subject to a significant degree of uncertainty. This uncertainty arise from limited knowledge about the system, mostly due to limitations in the experimental technology, and/or large variations in environmental and internal boundary conditions. The uncertainties become manifest in a only partially known interactome as well as unknown parameter values. 
             Despite of these uncertainties, in particular the revealing of key signaling mechanism is often possible. In this presentation an approach is introduced which allows the analysis of key properties of biological networks subject to uncertainties. Furthermore, the approach allows us to make guaranteed predictions. The methods are illustrated by studying a model of the NF-kB signal transduction pathway, involved in anti-apoptotic signaling.


Welcome to an exciting autumn of systems biology lectures!
Gunnar

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